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2021 Mercedes S-Class Review: The Ultimate Expression Of Luxury And Innovation

July 15, 2025 by John Leave a Comment

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The 2021 Mercedes-Benz S-Class is not merely a luxury sedan—it is a declaration of unmatched elegance, intelligence, and performance. Long regarded as the flagship model of the Mercedes-Benz lineup, the S-Class in 2021 sets new standards for comfort, technology, and engineering precision. With a refined silhouette, a reimagined cabin, and class-leading innovations, the 2021 S-Class redefines what it means to be a premium executive vehicle.

Bold Exterior Design With Aerodynamic Perfection

The exterior of the 2021 Mercedes S-Class embodies a modern interpretation of timeless design. Sleek proportions, muscular shoulders, and a distinctive grille highlight its commanding presence on the road. The car’s design is both sophisticated and aerodynamic, achieving a drag coefficient of just 0.22 Cd—one of the lowest in its class.

Key Exterior Highlights:

  • MULTIBEAM LED headlights with DIGITAL LIGHT technology for ultra-precise illumination
  • Long hood with a flowing roofline leading to a coupe-like rear
  • 19″ to 21″ alloy wheels available in various premium finishes
  • Flush door handles that extend automatically when the driver approaches
  • Panoramic sunroof with infrared-reflecting glass for optimized cabin comfort

Interior Excellence: The Future Of Luxury Cabins

Stepping inside the 2021 S-Class is like entering a digital sanctuary wrapped in handcrafted opulence. The cabin is a seamless blend of high technology and traditional craftsmanship, adorned with open-pore wood trim, fine Nappa leather, and ambient lighting that offers 64 customizable colors.

Interior Features That Define Class:

  • MBUX (Mercedes-Benz User Experience) with a 12.8-inch OLED central display
  • 12.3-inch digital instrument cluster with 3D effect
  • Advanced voice recognition system that responds to “Hey Mercedes”
  • Active ambient lighting integrated with driver assistance functions
  • Heated, ventilated, and massaging front and rear seats with memory settings
  • Burmester 4D surround sound system with 30 speakers and 1,750 watts

Unmatched Rear Seat Comfort

The rear cabin of the 2021 S-Class offers an experience on par with first-class airline travel. With optional Executive Line packages, rear occupants enjoy individual reclining seats, footrests, a rear MBUX tablet, and even heated armrests.

This makes the S-Class a true chauffeur-driven luxury car, favored by executives and dignitaries worldwide.

Powertrain And Performance: Smooth Yet Powerful

Underneath the elegant exterior lies a powerhouse of engineering. The 2021 S-Class offers a range of mild-hybrid powertrains designed for refined performance and optimal efficiency.

Engine Options:

  • S 500 4MATIC: 3.0-liter inline-6 turbocharged engine with EQ Boost
    • 429 horsepower and 384 lb-ft of torque
    • 0–60 mph in approximately 4.8 seconds
  • S 580 4MATIC: 4.0-liter V8 Biturbo with EQ Boost
    • 496 horsepower and 516 lb-ft of torque
    • 0–60 mph in just 4.4 seconds

Both models come with the 4MATIC all-wheel-drive system and a 9-speed automatic transmission for seamless shifting and better traction in all conditions.

Groundbreaking Technology And Driver Assistance

The 2021 Mercedes-Benz S-Class is the benchmark for automotive innovation. It includes the most advanced suite of driver-assistance technologies on the market, bringing the brand closer to autonomous driving.

Standout Tech Features:

  • Level 2 autonomous driving capabilities with Active Distance Assist DISTRONIC
  • Augmented Reality Navigation overlays directional graphics on a live camera feed
  • Head-up display with holographic projection
  • Rear-axle steering for a turning radius comparable to a compact car
  • Pre-Safe Impulse Side: Uses airbags to move occupants away from a crash zone

Digital Interface: MBUX Revolution

The next-generation MBUX system in the 2021 S-Class is among the most intuitive interfaces in the luxury segment. The central touchscreen, center console, rear-seat controls, and even the steering wheel are all digitized and tactile-sensitive.

  • Five screens available throughout the cabin
  • Natural speech recognition learns and adapts to individual preferences
  • Biometric authentication via fingerprint, facial recognition, or voice
  • Over-the-air updates keep systems fresh and functional

Safety And Driver Assistance Innovations

Safety has always been a priority in the S-Class, and the 2021 model builds on this legacy. It is one of the safest vehicles in the world with features that actively protect, alert, and even intervene on behalf of the driver.

Safety Suite Includes:

  • Active Lane Keeping Assist
  • Active Brake Assist with Cross-Traffic Function
  • Night View Assist PLUS with infrared camera
  • Evasive Steering Assist
  • Car-to-X communication, enabling vehicles to share road condition data

Ride Quality And Chassis Dynamics

The ride in the 2021 Mercedes S-Class is unmatched. Thanks to the new AIRMATIC air suspension with continuously adjustable damping and E-Active Body Control, the vehicle glides over imperfections like a magic carpet.

The optional E-Active Body Control scans the road ahead using cameras and adjusts suspension preemptively, ensuring the smoothest ride available in any luxury sedan.

Customization And Trims

Mercedes-Benz offers several trims and customization options to tailor the S-Class to individual tastes. Whether you desire a performance-focused build or chauffeur-level comfort, the configurations are nearly limitless.

Trim Options Include:

  • Luxury Line
  • AMG Line
  • Executive Rear Seat Package
  • Warmth and Comfort Package
  • Night Package with darkened exterior elements

Buyers can choose from over 15 exterior colors, 10 leather options, and numerous wood trims, making the S-Class one of the most customizable vehicles in its class.

Pricing And Value Proposition

Starting at around $110,000, the 2021 S-Class offers exceptional value when measured against its technology, luxury, and performance. The top-tier S 580 with Executive Line and full tech suite can exceed $140,000, but every dollar is accounted for in uncompromising quality and prestige.

Final Verdict: The Benchmark Of All Luxury Sedans

The 2021 Mercedes-Benz S-Class remains the gold standard for luxury sedans. Its combination of world-leading comfort, advanced technology, and dignified performance places it firmly at the pinnacle of automotive excellence. For those seeking the ultimate blend of prestige and innovation, there is simply no substitute.

FAQs

  • Q1: What is the fuel economy of the 2021 Mercedes S-Class?

A1: The S 500 delivers around 21 mpg city / 30 mpg highway, while the S 580 gets 17 mpg city / 25 mpg highway.

  • Q2: Does the 2021 S-Class support wireless Apple CarPlay and Android Auto?

A2: Yes, both are supported wirelessly as standard.

  • Q3: What are the most luxurious features in the S-Class rear seat?

A3: Reclining massage seats, heated armrests, ambient lighting, and personal tablets make it first-class all the way.

  • Q4: Can the 2021 S-Class drive itself?

A4: It features Level 2 autonomy, meaning it can steer, accelerate, and brake on its own under certain conditions.

  • Q5: Is the Mercedes S-Class better than the Maybach?

A5: The Maybach is even more luxurious and exclusive, but for most people, the S-Class hits the perfect balance of prestige and practicality.

See Also:

  • Mercedes-AMG E53: Where Performance Meets Precision
  • The Ultra-Rare Bentley Batur Convertible
  • Porsche Panamera – The Ultimate Expression Of Performance And Luxury

 

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